BDBM455338 N2-((1R,5S,8s)-3-(6-Chloropyrimidin-4-yl)-3-azabicyclo[3.2.1]octan-8-yl)-7-(4-fluorophenyl)-N4,5,5-trimethyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::US10730881, Example 5
SMILES CNc1nc(NC2C3CCC2CN(C3)c2cc(Cl)ncn2)nc2N(CC(C)(C)c12)c1ccc(F)cc1
InChI Key InChIKey=RDKVSARKLROBFD-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 455338
Affinity DataEC50: 31nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair